Born in 1975, USA.
Graduated from Oberlin College, Oberlin, OH in 1998.
Start at Stanford in fall 2000.
| ajmurphy at stanforddotedu
Born in 1975, USA.
|
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Interests in the StackLab: Heterogeneous and homogeneous oxidation catalysts
In general, my research is pursuing efficient manganese and iron catalytic
systems for oxygen transfer to alkanes and alkenes. My goals are to discover
catalysts that meet the following criteria: 1) are relative simple and
inexpensive to synthesize, 2) are operationally easy to use, 3) provide
high turnover numbers and frequency, 4) show high selectivity for desired
products. My systems are ultimately inspired by metalloenzyme systems,
but are not constrained by any specific enzyme site or reactivity. We believe
that bi- and tetra-dentate nitrogen ligands, which bind in a cis fashion,
can provide highly reactive catalysts similar to non-heme enzymes. Heterogenous
systems are being developed in parallel with homogenous systems in the
hopes of enhancing reactivity and catalyst stability.
Publications:
(6) Discovery and optimization of rapid
manganese catalysts for the epoxidation of terminal olefins
Murphy, A., Stack, T.D.P.
J. Mol. Catal., A: 2006; 251, 1-2, 78-88.
(5) Ligand and pH influence on manganese-mediated
peracetic acid epoxidation of terminal olefins
Murphy A.J., Pace A., Stack T.D.P.
Org. Lett. 2004,
6,
18,
3119-3122.
(4) Simple iron catalyst for terminal alkene
epoxidation
Dubois G., Murphy A.J., Stack T.D.P.
Org. Lett. 2003,
5,
14,
2469-2472.
(3) Efficient epoxidation of electron-deficient
olefins with a cationic manganese complex
Murphy A.J., Dubois G., Stack T.D.P.
J. Am. Chem. Soc.2003,
125,
18,
5250-5251.
(2) Remarkable affinity and selectivity for Cs+ and uranyl
(UO22+) binding to the manganese site of the apo-water
oxidation complex of photosystem II
Ananyev G.M., Murphy A., Abe Y., Dismukes G.C.
Biochemistry 1999, 38, 22, 7200-7209.
(1) ''Inorganic mutants'' of the water oxidation complex of Photosystem
II
Abe Y., Ananyev G.M., Murphy A., Zaltsman L., Mincer J., Dismukes G.C.
J. Inorg. Biochem. 1999, 74, 1-4, 114-114.